Predictors of Extubation Failure in Myasthenic Crisis

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Predictors of extubation failure in myasthenic crisis.

BACKGROUND The ideal timing for extubation of patients with myasthenic crisis (MC) and the factors that influence extubation outcome are not well established. OBJECTIVES To assess the risk of extubation failure in MC and to identify predictors of extubation failure. DESIGN We reviewed consecutive episodes of MC treated with endotracheal intubation from January 1, 1987, through December 31, ...

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Predictors of extubation outcomes following myasthenic crisis

Objective Myasthenic crisis (MC) is considered the most severe adverse event in patients with myasthenia gravis. The present retrospective study was performed to evaluate the predictors of clinical outcomes in patients with MC. Methods The medical charts of 33 patients (19 women, 14 men) with 76 MC attacks from 2002 to 2014 were retrospectively reviewed. Early extubation (≤7 days) and prolonged...

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Management of myasthenic crisis.

Sir, I read with interest the recent article by Murthy et al. It provides excellent data regarding the management and outcome of patients with myasthenic crisis. I would like to make certain observations. First, Murthy et al have utilized the neostigmine test for confirmation of diagnosis. I would like to emphasize that the edrophonium (Tensilon) test is an excellent alternative for this purpos...

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Noninvasive ventilation in myasthenic crisis.

BACKGROUND Myasthenic crisis (MC) is often associated with prolonged intubation and with respiratory complications. OBJECTIVES To assess predictors of ventilation duration and to compare the effectiveness of endotracheal intubation and mechanical ventilation (ET-MV) with bilevel positive airway pressure (BiPAP) noninvasive ventilation in MC. DESIGN Retrospective cohort study. SETTING Acad...

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Pulmonary Edema in Myasthenic Crisis

We report a previously asymptomatic 50-year-old lady who came with myasthenic crisis as initial presentation of myasthenia gravis. She developed pulmonary edema following intravenous immunoglobulin administration and had ischemic changes in ECG and left ventricular dysfunction on echocardiography. She improved with diuretics, dobutamine, and fluid restriction alone. This is the first report in ...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2008

ISSN: 0003-9942

DOI: 10.1001/archneur.65.7.929